COULD HEAD RADIATION TREATMENT RESULT IN DEPRESSION?

Could Head Radiation Treatment Result in Depression?

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Dr. Leland M. Heller

Biological Unhappiness

Could Head Radiation Treatment Result in Depression?
Could Head Radiation Treatment Result in Depression? COULD HEAD RADIATION TREATMENT RESULT IN DEPRESSION? Could Head Radiation Treatment Result in Depression?
Question:
I had a stroke in 2001 at 40 years old which damaged my balance and short term memory.  I'm now 43, retired on social security and can't shake my depression since.  Prozac after 1 year didn't make a difference.  I was told the stroke was caused by radiation therapy damage after a brain tumor removal from the cerebellum in 1981.  Do you think the radiation therapy from 20 years+ ago may have also done physical damage to cause may unshakable depression?  Do you have suggestions on how I can feel better?  I exercise at a gym religiosly 3+ days a week which helps bring my mood up to medium then falls until I exercise again? 
Thanks


Dr. Heller's Answer:
Assuming you didn't have mental health problems before the stroke AND that you have no active coronary artery disease, there's a moderate chance psychostimulants like Ritalin and Adderall can make a difference.  While the scientific literature is sketchy, I've seen it work on many stroke patients.

Here are some references that don't prove the point but show it might help:

Methylphenidate in early poststroke recovery: a double blind, placebo controlled study.
Arch Phys Med Rehab 1998 Sep

"Methylphenidate appears to be a safe and effective intervention in early poststroke rehabilitation that may expedite recovery."

Effects of methylphenidate on attentional function after traumatic brain injury.  A randomized, placebo-controlled trial. 
Am J Phys Med Rehabil 1997 Nov-Dec

"Methylphenidate produced a significant improvement in the speed of mental processing.  Most aspects of sustained attention, and measures of motor speed were unaffected.  Methylphenidate may be a useful treatment of traumatic brain injury, but is primarily useful for symptoms that can be attributed to slowed mental processing."


Could Head Radiation Treatment Result in Depression?



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Could Head Radiation Treatment Result in Depression?    Could Head Radiation Treatment Result in Depression?

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