Question:
Hello,
I am trying to find out some things
about Paxil and Zoloft. My boyfriend has been
on Paxil for about 2 months. Before that
he was on Zoloft for about 6 months, and went off
it because he didn’t like the way it made him feel.
To make a long story short: both
medications are bringing out anger. He never
used to show signs of rage and anger, and
now I am actually afraid that if we are in
public and someone says the wrong thing, he will
punch them. He isn’t as depressed as he
used to be, but now he is pent up, and sometimes
acting like a jerk (never to me, but to
strangers)---HELP!!
I have heard that SSRI’S can
have this effect. Does that mean he
should take something to counteract the anger, or
possibly is on the wrong medicine?
Thanks.
Dr. Heller's Answer:
The genetic cognitive generalized
anxiety disorder is usually the culprit. It’s an elevated
serotonin (S1A) receptor that’s increased
by SSRI medications like Paxil and Zoloft. This
increased anxiety can trigger anger, particularly
in those with the borderline personality disorder
although there are other possibilities such as
worsening of bipolar disorder.
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